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FACP. Colegio de médicos de Tarragona Nº 4305520 / fgcapriles@gmail.com

WORLD EMERGENCY MEDICINE SOCIETIES & RELATED

EMERGENCY MEDICINE DAY: MAY 27

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martes, 28 de junio de 2011

Hipercalcemia: TIPs del tratamiento

TRATAMIENTO DE LA HIPERCALCEMIA
Narrative review: Furosemide for Hypercalcemia: An Unproven yet Common Practice
LeGrand et al. Annals of Internal Medicine 2008; 149 (4): 259-263

1.- Bisphosphonates have supplanted all other drugs except corticosteroids for hypercalcemia of multiple myeloma (Body JJ. Current and future directions in medical therapy: hypercalcemia. Cancer. 2000;88:3054-8)
2.- The use of loop diuretics should be restricted to those patients who are in danger of fluid overload. Loop diuretics are not very effective in promoting significant renal calcium excretion, and may provoke volume depletion when used in patients whose volume deficit has not been reversed and who are not fully rehydrated (Mundy GR, Guise TA. Hypercalcemia of malignancy. Am J Med. 1997;103:134-45)
3.- Today, IV [intravenous] bisphosphonates are the standard therapy for hypercalcemia of malignancy (Pecherstorfer M, Brenner K, Zojer N. Current management strategies for hypercalcemia. Treat Endocrinol. 2003;2:273-92)