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FACP. Colegio de médicos de Tarragona Nº 4305520 / fgcapriles@gmail.com




Friday, May 25, 2012

Intoxicación por salicilatos

Emergency Department Management of the
Salicylate-Poisoned Patient
O’Malley G. Emerg Med Clin N Am 2007; 25: 333-346
"The term salicylate refers to any of a group of chemicals that are derived from salicylic acid. The best known is acetylsalicylic acid (aspirin). Acetylsalicylic acid is metabolized to salicylic acid (salicylate) after ingestion. The salicylates originally were derived from salicin, the active ingredient in willow bark, which Hippocrates used 2500 years ago for treating pain and fever Salicylates also occur naturally in many plants such as strawberries, almonds, and tomatoes. Poisoning by aspirin is common and is under-represented in poison center data, because it is often not recognized. The in-hospital mortality for unrecognized chronic aspirin poisoning is reportedly three times higher than if the diagnosis is made in the emergency department Familiarity with the clinical presentation during the various stages of acute and chronic aspirin poisoning is important for the practice of emergency medicine. The most challenging aspect of the clinical evaluation and management of the aspirin-poisoned patient may be recognition of the subtle signs and symptom of chronic, nonintentional aspirin overdose"