IV Combos Work for Agitation in the ED
By Todd Neale, Senior Staff Writer, MedPage Today - Published: September 15, 2012 - Reviewed by Zalman S. Agus, MD; Emeritus Professor, Perelman School of Medicine at the University of Pennsylvania
Action Points:
This randomized double-blind, placebo-controlled study was designed to compare time to sedation in the acutely agitated patient receiving midazolam following intravenous saline, droperidol or olanzapine.
Note that the study found that intravenous droperidol or olanzapine were effective as adjuncts to midazolam and decreased the time to adequate sedation compared with midazolam alone.