ACCF 2012 Expert Consensus Document on Practical Clinical Considerations in the Interpretation of Troponin Elevations
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Newby L et al. J Am Coll Cardiol. 2012;():. doi:10.1016/j.jacc.2012.08.969
..."What has become extremely clear is that much of the interpretation of the test results must consider the clinical context in which the measurement was made. For example, the interpretation of a positive troponin in a patient presenting with ischemic chest pain will (and must) be different from that in the patient undergoing a procedure or presenting with acute onset dyspnea, fever and hypotension, or renal failure. Furthermore, there is an increasing appreciation for the nonischemic versus ischemic etiologies of troponin release, and for the latter, an appreciation for differentiating the nuances of acute coronary syndromes (ACS) versus non-ACS etiologies. The most important nuance to understand is that an elevated troponin is a finding that represents the likely occurrence of myocardial necrosis and does not in and of itself provide any indication of the etiology..."