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sábado, 12 de enero de 2013


All Beta-Blockers Not Created Equal
By Todd Neale, Senior Staff Writer, MedPage Today
Published: January 11, 2013
Reviewed by F. Perry Wilson, MD, MSCE; Instructor of Medicine, Perelman School of Medicine at the University of Pennsylvania and Dorothy Caputo, MA, BSN, RN, Nurse Planner

"Action Points

  • Carvedilol is superior to other beta-1 selective beta-blockers in terms of all-cause mortality among patients with heart failure, according to this meta-analysis.
  • Be aware that the results of the meta-analysis were heavily driven by one large trial in each of the two patient subgroups examined."

Primary source: American Journal of Cardiology
Source reference:
DiNicolantonio J, et al "Meta-analysis of carvedilol versus beta 1 selective beta-blockers (atenolol, bisoprolol, metoprolol, and nebivolol" Am J Cardiol 2013; DOI: 10.1016/j.amjcard.2012.11.031.