Shift work and vascular events: systematic review and meta-analysis
Vyas M. y col. MNJ 2012; 345: e4800 doi: 10.1136/bmj.e4800 (Published 26 July 2012)
"What is already known on this topic
Shift work is associated with an increased risk of hypertension, metabolic syndrome, dyslipidaemia, and diabetes mellitus.
Disruption of circadian rhythm may predispose shift workers to vascular events; however, no organised systematic synthesis of all types of vascular events is available.
What this study adds
Shift work is associated with myocardial infarction, coronary events, and ischaemic stroke; the relative risks are modest, but population attributable risks are high.
These findings seem to be robust and insensitive to publication bias, quality of study, and socioeconomic status. Shift work is associated with an increased risk of hypertension, metabolic syndrome, dyslipidaemia, and diabetes mellitus.
Disruption of circadian rhythm may predispose shift workers to vascular events; however, no organised systematic synthesis of all types of vascular events is available.
What this study adds
Shift work is associated with myocardial infarction, coronary events, and ischaemic stroke; the relative risks are modest, but population attributable risks are high.
Conversely, shift work is not associated with increased rates of mortality (whether vascular cause specific or overall)"