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lunes, 14 de enero de 2013

Vasculitis pulmonares: parte 1

Pulmonary Vasculitis Update / Review
Part 1: Clinical Features & Diagnosis
By Brett Ley. MD. PulmCCM.org January 12, 2013

"Vasculitides are disorders of inflammation and necrosis of the blood vessel wall. In the lung, they can present in multiple ways: with alveolar hemorrhage, infiltrates, nodules, cavities, or airway disease. They are categorized by the size of vessel involved (small, medium, and large), the underlying immunologic mechanism (pauci-immune, immune-complex mediated), and associated systemic disease. The nomenclature for vasculitides has recently been revised by the 2012 International Chapel Hill Consensus Conference.
Although many forms of vasculitis have the potential to involve the lungs, the ANCA-associated vasculitides (AAVs) are a group of small-vessel vasculitides that commonly involve the respiratory tract and are the focus of a recent review in AJRCCM by Stephen Frankel and Marvin Schwartz"
Fuente: Frankel S. & Schwartz M. The Pulmonary Vasculidities.
AJRCCM 2012;186:216-224.