PulmCCM Sept 13, 2013 - Critical Care, Infectious Disease and Sepsis, Review Articles
"Vasopressors are provided for septic shock that does not respond to fluid resuscitation. Norepinephrine (Levophed), epinephrine, vasopressin, phenylephrine (Neo-Synephrine), and dopamine are the most commonly used vasopressors for septic shock.
Before vasopressors are begun for septic shock, the Surviving Sepsis Guidelines advise a minimum of 30 ml/kg of crystalloids (1.5-3 liters) be infused for most patients (Grade 1C) to ensure adequate fluid resuscitation. Some patients will require more IV fluids; fluid should be aggressively infused for as long as the patient continues to improve hemodynamically (ungraded recommendation). A portion of infused resuscitation fluid can be given as “albumin-equivalent” (Grade 1C)."
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