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FACP. Colegio de médicos de Tarragona Nº 4305520 / fgcapriles@gmail.com

WORLD EMERGENCY MEDICINE SOCIETIES & RELATED

EMERGENCY MEDICINE DAY: May 27

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lunes, 14 de julio de 2014

B Block Tox

SoBronEM - July 11. 2014 - By Marianne Sacasa, MD
"Beta-Adrenergic antagonists are used to treat hypertension, ischemic heart disease, heart failure, arrhythmias, migraine headache, tremor, portal hypertension, aortic dissection… the list goes on to da break of dawn.
  • Physiology: Competitive antagonism of beta receptor → decrease cAMP → decrease calcium → decrease contractility
  • Beta 1 Selective → depressed myocardial contractility, decreased automaticity in pacemaker cells, decreased conduction velocity.
  • Nonselective B Blocker→ bronchoconstriction, impaired gluconeogenesis, and decreased insulin release
  • Other properties: Lipophilicity and Membrane stabilizing activity (MSA)"
http://sobroem.com/2014/07/11/b-block-tox/