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lunes, 11 de agosto de 2014

Colchicina para pericarditis

R.E.B.E.L. EM - 11 AUG 2014 - By Chris Bond
"Acute and recurrent pericarditis are frequently diagnosed in the emergency department. Traditionally, treatment has consisted of anti-inflammatory medications (eg. ASA or NSAIDs) or corticosteroids. Colchicine is an underutilized therapy for pericarditis and provides significant benefit when combined with NSAIDs/ASA. Addition of colchicine to standard therapy results in earlier reduction in pericarditis symptoms, greater remission at 1 week, and reduces the rate of recurrent pericarditis. Let’s review the literature for colchicine for treatment of pericarditis.
Clinical Bottom Line
Unless there are contraindications to its use, colchicine should be prescribed in all cases of uncomplicated pericarditis, along with standard therapy of ASA/NSAID and a PPI. Glucocorticoids should be prescribed with caution, as they are an independent risk factor for pericarditis recurrence."