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FACP. Colegio de médicos de Tarragona Nº 4305520 / fgcapriles@gmail.com

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martes, 21 de julio de 2015

Canabinoides sintéticos

The Poison Review. July 20, 2015
Synthetic Cannabinoid—Related Illnesses and Deaths. 
Trecki J et al. N Engl J Med 2015 Jul 9;373:103-107. Reference
"As the authors point out in this interesting article, there has been a recent surge in reports of fatalities and severe toxicity from synthetic cannabinoids (SCs). This is likely from a combination of increased incidence and more diligent surveillance.
The most interesting part of the paper is the Table, that lists recent cases involving severe toxic effects from SCs, including 20 deaths. The specific SCs involved in the fatal cases include MAB-CHMINACA, AB-PINACA, XLR-11, ADB-PINACA, and AM-2201.
the authors also highlight the difficulties involved in dealing with these new agents, especially the time required to develop specific laboratory tests and the rapidly changing mix of chemicals being marketed as SCs. Worth reading."
www.thepoisonreview.com/2015/07/20/serious-toxicity-and-fatalities-from-synthetic-cannabinoids/

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The Poison Review. June 13, 2015
Increase in Reported Adverse Health Effects Related to Synthetic Cannabinoid Use —United States, January-May 2015. MMWR 2015 Jun 12;64:618-619. Full Text
"I have to say that this report shocked me some. Although I was aware of an increased number of news reports of incidents related to synthetic cannabinoids, I really had no idea the increased number of cases involving exposures reported to poison centers with major adverse effects and death were so dramatic"
http://www.thepoisonreview.com/2015/06/13/dramatic-recent-increase-in-cases-and-deaths-associated-with-use-of-synthetic-cannabinoids/
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For a very good discussion about these agents, see Alice Walton’s 2014 article “Why Synthetic Marijuana Is More Toxic To The Brain Than Pot” on the Forbes website"