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FACP. Colegio de médicos de Tarragona Nº 4305520 / fgcapriles@gmail.com


STEMI Equivalents

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sábado, 31 de octubre de 2015


SCANCRIT - Posted on November 26, 2014 by Thomas D
"We’ve been waiting for the AVOID study, since we mentioned it a few years ago in another post on the harm of excessive oxygen. AVOID (Air Versus Oxygen in Myocardial Infarction). Now, it’s out. As expected, it shows that unnecessary oxygen supplement worsens outcome. The surprise is just how big a difference it makes! In this study, too much oxygen increased recurrent MI fivefold!
Avoiding hyperoxemia isn’t new. Normoxemia has been a trend, but lacked hard evidence in form of an RCT, and the reflex-O2-mask in ED has been hard to fight. Right now, the full AVOID article has yet to be released, but the results have just been presented at AHA’s congress in Chicago last week. And AHA has posted a video interview with Dr. Stub, one of the investigators of the AVOID trial, on the results, as well as posted his presentation slides here.

Supplemental oxygen therapy in patients with STEMI but without hypoxia increased early myocardial injury and was associated with larger myocardial infarct size assessed at six months."