EM Didactics - December 21, 2015 - By Lakshay Chanana
"This episode talks about diabetic ketoacidosis. Some key points on how insulin maintains normoglycemia before we end with a couple of clinical take home points.
Key Points:
- Insulin shifts GLUT4 from the cytoplasm to the cell membrane to facilitateglucose uptake.
- Majority of KB produced in DK is Beta Hydroxybutyrate but urine dipsticks donot detect this. Go one step further and ask for serum ketones.
- Treatment of DKA (in order)
- Hydration then watch potassium and only then Insulin infusion (No bolus)
- Ask yourself - What is the precipitating event?
- Venous pH is acceptable"
http://emdidactic.blogspot.com.es/2015/12/understanding-diabetic-ketoacidosis.html