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EMU 365: Best Emergency Medicine Articles of the Year 2018

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viernes, 22 de enero de 2016

Purple glove syndrome

TPR - January 21, 2016
Ref. Purple Glove Syndrome after Phenytoin or Fosphenytoin Administration: Review of Reported Cases and Recommendations for Prevention. Garbovsky LA et al. J Med Toxicol 2015 Dec;11:445-459.  Abstract
Purple glove syndrome (fda.gov)
"Purple glove syndrome (PGS) is an uncommon adverse drug reaction to parenteral administration of phenytoin or fosphenytoin marked by severe progressive soft tissue discoloration, swelling and pain in the distal extremity into which the drug was infused.
This extremely well done and comprehensive paper will tell you all you need to know (well, probably more than you need to know) about our understanding of the syndrome to date."