Thursday, March 31, 2016

Mannitol vs. Hypertonic Saline for Elevated ICP

SOCMOB BLog - March 29, 2016 by Admin
"This week’s version of the Skeptics Guide to Emergency Medicine – Hot off the Press was released yesterday and covers a systematic review of mannitol vs. hypertonic saline solution for elevated ICP. We spoke with the lead author of the study, Dr. Elyse Pelletier, and got a chance to ask her questions about the particulars of the study. You can check out the SGEM post, show notes and the podcast here.
Here is a link to the original article, which is free and open access from the Canadian Journal of Emergency Medicine (CJEM).
Major results
There were two primary outcomes in this study; death and control of ICP.
Unfortunately, there was no improvement in mortality or ICP control when using hypertonic saline vs. mannitol."