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lunes, 23 de mayo de 2016

Platelets for Intracranial Haemorrhage

Intracranial Haemorrhage Platelet
St Emlyn´s - May 22, 2016 - By Simon Carley
"Unfortunately, many patients with haemorrhagic strokes are on antiplatelet drugs such as aspirin and clopidogrel, drugs with long durations of effect on platelet function. Understandably then there has been much interest in determining whether improving platelet function in these patients improves outcome, with the most obvious therapy being platelet infusion. Platelet infusion has been proposed as a way of counteracting the effect of antiplatelet drugs in the acute phase of intracranial bleeding…. but does it work?
It’s a question tackled by researchers in the UK, Netherlands and France in the New England Journal of Medicine. The PATCH study was designed to specifically answer the question of whether patients who have a non-traumatic intracranial bleed, who are on antiplatelet drugs, benefit from platelet transfusions...
The bottom line:
Unless new evidence emerges, new trials are published, or alterations in therapy are proposed then if your patient has a non-traumatic intracerebral bleed, and they are on clopidogrel, aspirin or some other antiplatelet drug then don’t prescribe the platelets.
The bottom line is that whichever way the authors looked at the data the indication is that platelet infusion worsens outcome."