Síguenos en Twitter     Síguenos en Facebook     Síguenos en Google+     Síguenos en YouTube     Siguenos en Linkedin     Correo Grupsagessa     Gmail     Yahoo Mail     Dropbox     Instagram     Pinterest     Slack     Google Drive     Reddit     StumbleUpon     Print


Mi foto
FACP. Colegio de médicos de Tarragona Nº 4305520 / fgcapriles@gmail.com


EMU 365: Best Emergency Medicine Articles of the Year 2018

Buscar en contenido


lunes, 27 de junio de 2016


The Bottom Line - June 24, 2016 - By Duncan Chambler
Erythromycin for Gastric Emptying in Patients Undergoing General Anesthesia for Emergency Surgery. Czarnetzki. JAMA Surg. 2015; 150:730-7. doi:10.1001/jamasurg.2015.0306
"Clinical Question
  • In adult patients undergoing general anaesthesia for emergency surgery, does pre-medication with erythromycin compared to placebo reduce the volume of gastric content?
The Bottom Line
  • This single centre RCT has methodological concerns that reduce the internal validity and external generalisability
  • Erythromycin may reduce residual gastric content and acidity but this trial does not demonstrate sufficient statistical significance to reject the null hypothesis
  • Any benefit occurs at the expense of unpleasant side effects with equal incidence to the intended benefit
  • Whilst the authors should be commended for thinking laterally and investigating this novel idea, I shall not be using erythromycin prior to rapid sequence induction of anaesthesia"