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Wednesday, July 6, 2016

Alternatives to phentolamine for vasopressor extravasation

Posted on August 11, 2015 - By Pharmacy Joe
Phentolamine (1)
"11/4/15 Update: Phentolamine is available again!
The rest of the post is un-edited, but check with your purchaser to see if you can get phentolamine now.
Another one bites the dust. 
Phentolamine is no longer manufactured. 
Phentolamine has now made ASHP's list of drugs no longer available.
This information is critical to communicate to emergency medicine and critical care practitioners, as the risk:benefit of peripheral vasopressor therapy changes without the availability of this extravasation antidote.
This doesn't change my any port in a storm philosophy of peripheral vasopressor use, but it will make me advocate for the placement of a central line sooner in patients where I see peripheral vasopressor use continuing for more than a few hours..."
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