R.E.B.E.L.EM - July 14, 2015 - By Waye V
"Recently, there has been a lot of buzz about the use of topical tranexamic acid for epistaxis or oral bleeds on multiple social media platforms. Everyone seems so happy that it works so well, but we thought we would look through the literature and see what the evidence for use of topical tranexamic acid (TXA) is and how best to compound it for these clinical dilemma. We performed a PubMed, and Ovid search using the terms “topical” AND/OR “oral solution” AND/OR “intranasal” PLUS “tranexamic acid” to answer our questions at hand.
Clinical Questions:
- What is the literature regarding the use of topical tranexamic acid for epistaxis or oral bleeds?
- How should it be compounded and administered safely and effectively?"