Friday, August 12, 2016

Heparin Induced Thrombocytopenia (HIT)

emDocs - August 11, 2016 - Authors: Murnan S and Slama R
Edited by: Simon E, Long B & Koyfman A
  • "What is HIT?
  • The Clinical Presentation of HIT: A Spectrum of Disease
  • Alright, that sounds great, but why should I care about HIT in the emergency department?
  • I hear that HIT is often misdiagnosed, are there any tools to help me in determining how likely it is that my patient actually has HIT?
  • Key Points Regarding the 4T Score
  • Treatment and Management of HIT in the Emergency Setting
  • Laboratory Studies for The Confirmation of HIT
  • If the Shoe Doesn’t Fit
  • Summary
    1. HIT is relatively rare, but can occur even after receiving the smallest dose of heparin.
    2. Despite thrombocytopenia, HIT is a prothrombotic state that can cause disastrous vascular complications.
    3. In the ED, clinical history and a CBC can be suggestive of the diagnosis. Use the 4T Score and consult as appropriate.
    4. Suspect HIT? Treatment = stop heparin and discuss an alternative agent for anticoagulation with a hematologist."