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lunes, 22 de agosto de 2016

Lithium poisoning

The Poison Review - August 19, 2016
Ref: Lithium Poisoning: State of the Art. Baird-Gunning J et al. J Intensive Care Med 2016 Aug 11 [Epub ahead of print]
This is a very good paper, the best comprehensive review I can remember reading on lithium. It is up to date, with 78 references as recent as 2015. A major reason I liked it so much is that the authors are quire frank about how much we don’t know, and resist giving, for instance, mandates about when to start hemodialysis based on lithium levels. This is a temptation that the authors of the recent ExTRIP review succumbed to. Interestingly, the two papers share an author (Sophie Gosselin).
However, I think the authors missed — or at least failed to emphasize — a key point. With lithium poisoning, as with all toxicology cases, the key to successful treatment begins with basic ABCs and supportive care. This includes adequate hydration, which is crucial..."