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FACP. Colegio de médicos de Tarragona Nº 4305520 / fgcapriles@gmail.com


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jueves, 4 de agosto de 2016

Vasopressin vs Norepinephrine on KF (VANISH Trial)

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Gordon A et al. JAMA. 2016; 316(5): 509-518. -  doi:10.1001/jama.2016.10485
To compare the effect of early vasopressin vs norepinephrine on kidney failure in patients with septic shock.
Conclusions and Relevance 
Among adults with septic shock, the early use of vasopressin compared with norepinephrine did not improve the number of kidney failure–free days. Although these findings do not support the use of vasopressin to replace norepinephrine as initial treatment in this situation, the confidence interval included a potential clinically important benefit for vasopressin, and larger trials may be warranted to assess this further."
Trial Registration clinicaltrials.gov Identifier: ISRCTN 20769191