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Monday, October 17, 2016

Liver Disease and Hemostasis

emDocs - October 16, 2016 - Author: Robertson J - Edited by: Koyfman A
..."Given the large number of components of hemostasis that are produced by the liver, it is not surprising that patients with cirrhosis are considered to have abnormal hemostasis. However, the pathophysiology is complicated and patients with cirrhosis may actually be prone to clotting just as much as bleeding. In fact, patients with cirrhosis may even be slightly more at risk for clotting than those without liver disease... 
Conclusions
While more studies need to be conducted on bleeding and clotting risk in patients with cirrhosis, especially with newer, more sensitive tests for the coagulation system, the point of this review is that patients with cirrhosis CAN form clots. Thus, if there are any signs and/or symptoms of a blood clot in your next patient with cirrhosis, then adequate workup should be obtained."