PulmCrit (EMCrit)
PulmCrit - October 24, 2016 by Josh Farkas

- "Meropenem doesn’t cause anaphylaxis.
- Meropenem probably isn’t cross-allergic with penicillin, due to structural differences in its side chains and beta-lactam core.
- It is widely quoted that patients with penicillin allergy have a ~1% risk of reaction to meropenem. This information is based on non-validated skin testing to meropenem, which is probably incorrect.
- Prospective studies have proven the safety of giving meropenem to patients with a history of anaphylaxis to penicillin."