emDocs - September 20, 2017 - Authors: William G & Riehle C
Edited by: Koyfman A and Long B
"Take Home Points
- History and presentation are perhaps the most important and may provide you with enough evidence of disease progression “through time and space” to reach a diagnosis.
- MRI will be needed at some point to look for asymptomatic lesions and establish a baseline for future monitoring.
- LPs can be used if an MRI is unavailable or unequivocal, but sensitivity is often low in CIS, and specificity is only high when you can rule out other causes of an elevated Ig Index.
- Treatment consists of high dose steroids +/- β Interferon if you have reason to believe this is a CIS."