PEP Dosing for HIV
  • Emtricitabine/tenofovir (Truvada): 200mg/300mg (1 tablet) PO daily
  • Raltegravir (Isentress): 400 mg PO twice daily
Because the preventative effectiveness of these medications decline over time, it is critically important to administer the first dose of each in the Emergency Department in a timely fashion. Evidence extrapolated from animal data suggests that efficacy of HIV post exposure medications decreases greatly 72 hoursafter exposure and should not be provided."