
emDocs - November 5, 2018 - Author: Murchison C - Edited by: Koyfman A and Long B
..."Takeaways:
- The evidence for acidosis being harmful is primarily based on in vitro studies. Clinical data show acidosis may not be as harmful as we think.
- Sodium bicarbonate therapy creates excess CO2 which must be quickly exhaled. If a patient is not adequately ventilating they will become more acidotic when given sodium bicarbonate therapy.
- There are only two clinical trials on using sodium bicarbonate in cardiac arrest, both show no benefit. The AHA no longer recommends its use in ACLS."