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Sunday, December 2, 2018

D-Dimer in Pregnancy

R.E.B.E.L.EM - November 29, 2018 - By Rick Pescatore


..."Authors’ Conclusion:
In pregnant women with suspected PE, a diagnostic strategy involving assessment of pretest clinical probability, D-dimer measurement, bilateral leg CUS, and CTPA can safely rule out the disease, with a 3-month thromboembolic rate of 0.0% (95% CI, 0.0% to 1.0%).
Clinical Take Home Point: Among pregnant women presenting with concern for pulmonary embolism in pregnancy, who have a low or medium pre-test probability of PE, a negative D-dimer can safely rule out the disease, though will only be helpful in a small proportion of patients."