The Bottom Line - October 19, 2018 - By Duncan Chambler
Apfel. NEJM 2004;350:2441-2451. doi:10.1056/NEJMoa032196
"The Bottom Line
- This landmark trial provides good evidence to guide clinical practice and communication with patients
- Beneficial interventions include: ondansetron, dexamethasone, droperidol, total intravenous anaesthesia (TIVA) with propofol, and avoidance of nitrous oxide
- This trial did not include regional anaesthesia interventions with opiate-sparing effects, which warrant further investigations"