R.E.B.E.L.EM - Januar7 07, 2019 - By Lakshmi N. Saladi
"Author’s Conclusion:
Among adult patients in the ICU who were at risk for gastrointestinal bleeding, mortality at 90 days and the number of clinically important events were similar in those assigned to pantoprazole and those assigned to placebo
Clinical Take Home Point:
Though no proven mortality benefit, the reduced incidence of clinically significant GI bleed without increase in infectious and cardiovascular adverse effects suggests a potential benefit of pantoprazole in selected critically ill patients with multiple risk factors for GI bleed"