Síguenos en Twitter       Síguenos en Facebook       Síguenos en YouTube       Siguenos en Linkedin       Correo Grupsagessa       Gmail       Yahoo Mail       Dropbox       Instagram       Pinterest       Slack       Google Drive       Print       StumbleUpon

SOBRE EL AUTOR **

Mi foto
FACP. Colegio de médicos de Tarragona Nº 4305520 / fgcapriles@gmail.com

WORLD EMERGENCY MEDICINE SOCIETIES & RELATED

EMERGENCY MEDICINE DAY: May 27

Buscar en contenido

Contenido:

martes, 12 de marzo de 2019

DEXACET

PulmCrit (EMCrit)
PulmCrit - March 11, 2019 - By Josh Farkas
"Summary: The Bullet
  • Acetaminophen has previously been shown to be an effective analgesic which can reduce opioid consumption.
  • DEXACET shows that in a cohort of critically ill post-cardiothoracic surgery patients, IV acetaminophen reduced the incidence of delirium. This suggests that acetaminophen use may offer meaningful, patient-oriented benefit.
  • Although DEXACET was performed with IV acetaminophen, other studies have found equivalent efficacy between either oral or intravenous forms.
  • Acetaminophen is probably an under-utilized analgesic among critically ill patients. For maximal efficacy, oral acetaminophen should be given in substantial doses in a scheduled fashion (e.g. 1 gram q6-q8 hours scheduled, not 650 mg q8hr PRN).
  • DEXACET isn’t incredibly robust statistically (fragility index of two). However, it validates longstanding principles of analgesia (specifically, the “analgesic ladder”). Until further evidence is available, it’s sensible to use these principles in clinical practice. This isn’t a revolution, but rather a reminder of first principles."