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FACP. Colegio de médicos de Tarragona Nº 4305520 / fgcapriles@gmail.com

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jueves, 11 de abril de 2019

Reverse anticoagulation with warfarin

CanadiEM
CanadiEM -  By Matthew Nicholson - April 2, 2019
"Main Messages
  • In major bleeding or urgent major procedures patients anticoagulated on warfarin the standard of care is co-administration of vitamin K (10 mg IV) and PCCs
  • PCCs are typically dosed based by INR +/- weight. An empiric dose if the INR is not known is typically 2000 IU.
  • Frozen plasma is inappropriate for warfarin reversal unless PCCs are unavailable (which should generally not be the case) or the patient has had a previous reaction to heparin (PCCs contain heparin)"