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FACP. Colegio de médicos de Tarragona Nº 4305520 / fgcapriles@gmail.com

WORLD EMERGENCY MEDICINE SOCIETIES & RELATED

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miércoles, 3 de abril de 2019

tPA Window in AIS

R.E.B.E.L.EM - By Salim rezaie - April 01, 2019
..."Author Conclusion: “In patients with acute stroke with an unknown time of onset, intravenous alteplase guided by a mismatch between diffusion-weighted imaging and FLAIR in the region of ischemia resulted in a significantly better functional outcome and numerically more intracranial hemorrhages than placebo at 90 days.” 
Clinical Take Home Point: In this multicenter randomized trial of patients with strokes of unknown time onset, the use of tPA resulted in a 11% improvement in neurologic outcomes at 90 days, and although not statistically significant also resulted in more death and more ICH."