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WORLD EMERGENCY MEDICINE SOCIETIES & RELATED

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miércoles, 15 de mayo de 2019

Risk of reversing anticoagulation

CanadiEM
CanadiEM - May 14, 2019 - By Andrew Shih
"...Main Messages
  • The main risk of reversing anticoagulant is typically thrombosis, where much of the risk is due to the underlying prothrombotic state rather than the reversal agent itself
  • Thrombosis risks in different meta-analyses for warfarin reversal with PCCs +/- vitamin K are reported to be < 5%
  • The thrombosis risk after use of TXA is likely minimal, though most studies assessing its use in bleeding excluded patients with risk factors for thrombosis"
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