Emergency Medicine News - December 2019; 41 (12): 16
doi: 10.1097/01.EEM.0000616476.30357.18
..."Contrary to widespread belief, IV procainamide is more effective and safer than IV amiodarone for the acute conversion of VT. (Am J Emerg Med. 2019;37[7]:1340; Acad Emerg Med. 2019;26[9]:1099, http://bit.ly/2p6hz7Y; Eur Heart J. 2017;38[17]:1329, http://bit.ly/2Vx0Nuw; Emerg Med J. 2015;32[2]:161.)
IV procainamide is the only agent that carries a class IIA indication for the pharmacologic conversion of VT, and it is listed ahead of IV amiodarone (class IIB) in the ACLS guidelines. (Am J Emerg Med. 2019;37[7]:1340; Acad Emerg Med. 2019;26[9]:1099, http://bit.ly/2p6hz7Y; Eur Heart J. 2017;38[17]:1329, http://bit.ly/2Vx0Nuw; Emerg Med J. 2015;32[2]:161; Circulation. 2010;122[16 Suppl 2]:S345; http://bit.ly/2nEfks4.)..."