REBEL Crit - December 12, 2019 - By Salim Rezaie
..."Author Conclusion: “In conclusion, the SS administration method is simple and no less effective than the TS method. Physicians should consider using the SS method particularly if no stopcock is available or if only a single-port-IV can be used for drug administration. Further randomized control studies should be completed to validate these results.”
Clinical Take Home Point: From a pragmatic standpoint, single syringe adenosine makes sense, and although we now have two small studies that show single syringe adenosine to be non-inferior to two syringe adenosine, we have to be cautious about making robust conclusions based on this level of evidence. In this study we don’t know the location of IVs, the two syringe technique used, what other medications were given, and the numbers are simply too small to make any comments on adverse events."