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FACP. Colegio de médicos de Tarragona Nº 4305520 / fgcapriles@gmail.com

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viernes, 20 de diciembre de 2019

Sodium Bicarbonate for Toxicology

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emDocs - December 19, 2019 - By Tyler Siekmann
..."Take Home Points:
  • Sodium bicarbonate can be a useful therapy in toxic ingestions of multiple compounds including: sodium channel blocking agents, salicylates and toxic alcohols.
  • Primary mechanisms of action include:
    • Overwhelming of the sodium channel blockades
    • Alkalizing serum and urine pH to limit toxicity and enhance elimination
  • Treatment should be started with bolus dosing of 1-2 mEq/kg of 8.4% NaHCO3.
  • Endpoints of treatment include: QRS < 100 msec, pH > 7.5, Na+ > 150mEq or clinical improvement."