R.E.B.E.L. Crit - April 06, 2020 - By Salim Rezaie
"Paper: Zhang Y et al. Intravenous Versus Intraosseous Adrenaline Administration in Out-of-Hospital Cardiac Arrest: A Retrospective Cohort Study. Resuscitation 2020. PMID: 31982506
Author Conclusion: “Compared with the IO approach, the IV approach appears to be the optimal route for adrenaline administration in advanced life support for OHCA during prehospital resuscitation.”
Clinical Take Home Point: This study should not change your practice of IV vs IO access in OHCA. Future randomized trials of access are needed to clarify this situation. If you are using IO access in cardiac arrest you want to go as proximal to the central circulation as possible, which is most commonly the humeral IO."