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FACP. Colegio de médicos de Tarragona Nº 4305520 / fgcapriles@gmail.com

WORLD EMERGENCY MEDICINE SOCIETIES & RELATED

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jueves, 18 de junio de 2020

NMDA Encephalitis

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emDocs - June 18, 2020 - By Furmick J, Murphy C
Reviewed by: Santos C; Koyfman A and Long B
"Anti-NMDA receptor encephalitis is a very specific autoimmune mediated reaction against the NMDA receptor that leads to down regulation of the receptor presenting as a variety of psychiatric and neurologic symptoms. Originally described as a paraneoplastic syndrome and seen exclusively in women with ovarian teratomas, it has since been described in those without tumors...

"Key points:

  • Anti-NMDA receptor encephalitis is an autoimmune reaction targeting the NMDA receptor.
  • Patients present with both psychiatric and neurologic symptoms.
  • 50% of cases are associated with ovarian teratomas.
  • Labs and imaging can be normal.
  • Treatment includes steroids + IVIG or plasmapheresis."