emDocs - November 30, 2020 - By Faiz Ahmed and Brian Meier
Reviewed by: Andrew Grock; Alex Koyfman; Brit Long
"Pearls:
- Consider decompensated hypothyroidism in anyone with altered mental status associated with hypothermia, bradycardia, and hypotension, especially for an elderly female in the winter months.
- Work up and treat both the precipitating event and the hypothyroidism simultaneously.
- The diagnosis of decompensated hypothyroidism is DO NOT wait for laboratory confirmation to initiate treatment.
- First line treatment is with IV Hydrocortisone (100mg) and IV thyroxine (T4) 200-400 mcg."