WORLD EMERGENCY MEDICINE SOCIETIES & RELATED

Search

Content:

Saturday, March 13, 2021

Serotonin Syndrome

EmDocs - March 13, 2021 - Andrea Nillas
Reviewed by: Kerollos Shaker, Nancy Onisko, Alex Koyfman, Brit Long
“Pearls:
  • Consider with history of polypharmacy, antidepressant, or opioid use
  • Presentation has fast onset and resolution
  • Clonus is a key physical exam finding
  • Hyperthermia, seizures, and rhabdomyolysis indicate severe serotonin syndrome
  • Treatment is supportive, targeting hyperthermia and agitation”