FIRST10EM - By Justin Morgenstern - March 1, 2021
“The paper
Post R, Germans MR, Tjerkstra MA, et al; ULTRA Investigators. Ultra-early tranexamic acid after subarachnoid haemorrhage (ULTRA): a randomised controlled trial.Lancet. 2021 Jan 9;397(10269):112-118. doi: 10.1016/S0140-6736(20)32518-6. Epub 2020 Dec 23. PMID: 33357465 NCT02684812
Bottom line
This is the largest RCT to date looking at TXA in subarachnoid hemorrhage, and based on these results, it should not be prescribed routinely.”