The Skeptics Guide to EM - By admin - March 13, 2021
Reference: Post et al. Ultra-early tranexamic acid after subarachnoid haemorrhage (ULTRA): a randomised controlled trial. Lancet 2021
“CLINICAL QUESTION: DOES RAPID ADMINISTRATION OF TRANEXAMIC ACID IN PATIENTS WITH CT CONFIRMED SAH IMPROVE CLINICAL OUTCOME?
KEY RESULT: NO SUPERIORITY OF TXA COMPARED TO USUAL CARE FOR PATIENTS WITH A SUBARACHNOID HEMORRHAGE.
SGEM BOTTOM LINE: TXA USE IN SUBARACHNOID HEMORRHAGE DOES NOT PRESENTLY HAVE SUFFICIENT EVIDENCE OF IMPROVING PATIENT OUTCOMES TO RECOMMEND ITS ROUTINE USE.”