REBEL EM - May 20, 2021 - By Salim Rezaie
Paper: Kofoed KF et al. Prognostic Value of Coronary CT Angiography In Patients With Non-ST-Segment Elevation Acute Coronary Syndromes. JACC 2021. PMID: 33632478 [Access in Read by QxMD]
“Clinical Question: Is CCTA equivalent to invasive coronary angiography (ICA) for risk assessment in patients with non-ST-segment elevation acute coronary syndrome (NSTEACS)?
Author Conclusion: “Coronary CTA is equivalent to ICA for the assessment of long-term risk in patients with NSTEACS.”
Clinical Take Home Point: This multicenter observational substudy from the VERDICT trial shows that CCTA can identify severity and extent of CAD in an equivalent fashion to ICA in assessing long-term risk in patients with NSTEACS. HOWEVER, without individual patient data, evaluating false negatives, and false positives, statistically significant hazard ratios do not help guide us on what to do at the bedside. We should not be substituting CCTA for ICA based on this data.”