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Monday, June 21, 2021

Therapeutic hypothermia

First10EM - By Justin Morgenstern - June 21, 2021
The paper
Dankiewicz J, Cronberg T, Lilja G, et al: TTM2 Trial Investigators. Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest. N Engl J Med. 2021 Jun 17;384(24):2283-2294. doi: 10.1056/NEJMoa2100591. PMID: 34133859 NCT02908308
„Bottom line
This large RCT demonstrated no benefit from ‘therapeutic’ hypothermia as compared to managed normothermia. To date, there is no evidence that managed normothermia is any better than no temperature management at all. That study probably needs to be done, but until then, temperature should not be a priority in post-arrest care“