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FACP. Colegio de médicos de Tarragona Nº 4305520 / fgcapriles@gmail.com

WORLD EMERGENCY MEDICINE SOCIETIES & RELATED

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Tuesday, October 5, 2021

Balanced vs 0.9% Saline Solution

SGEM#347 - By Admin - October 03, 2021
Reference: Zampieri et al. Effect of Intravenous Fluid Treatment With a Balanced Solution vs 0.9% Saline Solution on Mortality in Critically Ill Patients: The BaSICS Randomized Clinical Trial. JAMA 2021
CLINICAL QUESTION: DOES ADMINISTRATION OF A BALANCED SOLUTION (PLASMA-LYTE 148) DURING INTENSIVE CARE UNIT (ICU) STAY, COMPARED WITH SALINE SOLUTION, RESULT IN IMPROVED 90-DAY SURVIVAL IN CRITICALLY ILL PATIENTS?
KEY RESULTS: NO SIGNIFICANT INTERACTION BETWEEN FLUID TYPE OR INFUSION RATE FOR THE PRIMARY OUTCOME OF DEATH AT 90 
SGEM BOTTOM LINE: IN ADULT ICU PATIENTS AT RISK FOR KIDNEY INJURY, ADMINISTERING MODEST VOLUMES OF PLASMALYTE 148 VERSUS NORMAL SALINE, AT FAST OR SLOW INFUSION RATES, DID NOT INFLUENCE 90-DAY MORTALITY.