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Tuesday, July 19, 2022

Blood glucose rise with DW50

EM Pharm Pearls - July 18, 2022 - By: Bryan D. Haye
A common question is how much should we expect the blood glucose concentration to increase after dextrose 50% (D50) administration. Fortunately, there is an answer from 3 studies.
Take Home Points
  • Glucose concentrations increase 4-6 mg/dL per gm of dextrose administered50 mL of D50 = 25 gm = expected 100-150 mg/dL glucose rise
  • D50 rescue glucose is short-lived (30 minutes)
  • If the blood glucose does not respond as anticipated, investigate further (e.g., IV decannulation)