Saturday, August 20, 2022

N-ATBs in Mild Acute Diverticulitis

REBEL EM - By James C. Fletcher - August 18, 2022
The Paper: Mora-López, L. et al. Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO Study). Annals of Surgery, 2021. PMID: 34183510 [Access on Read by QxMD]
Clinical Question: Is it necessary to prescribe antibiotics to all patients undergoing outpatient management for mild diverticulitis as identified on CT scan?
Author Conclusion:Nonantibiotic outpatient treatment of mild AD is safe and effective and is not inferior to current standard treatment.”
Clinical Bottom Line: Otherwise healthy patients presenting to the Emergency Department with mild acute diverticulitis, no signs of severe infection/sepsis, and who achieve good symptom control in the ED may be discharged home with symptomatic management and close follow-up only, and may not require antibiotic therapy.