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Tuesday, September 6, 2022

BP & O2 Target with ROSC

REBEL Crit - By Salim Rezaie - September 05, 2022
Clinical Take Home Point: 
In comatose adult patients, with presumed cardiac etiology of their cardiac arrest, with ROSC…
  • There appears to be no difference between a restrictive vs liberal oxygenation target regarding the incidence of death or severe disability or coma at 90 days.
    • will continue to titrate FiO2 to maintain a PaO2 range of 68 to 105mmHg (based on this trial) or an SpO2 of 90 to 95% (my bedside practice) in the post arrest setting.
  • There appears to be no difference between targeting a lower mean arterial pressure (63mmHg) vs a higher mean arterial pressure (77mmHg) regarding the incidence of death or severe disability or coma at 90 days.
    • I will continue to target a mean arterial pressure of ≥65mmHg in the post arrest setting.