SGEM #389 - By admin - January 14, 2023
Reference: Razi et al. Dexamethasone and ketorolac compare with ketorolac alone in acute renal colic: A randomized clinical trial. AJEM 2022
CLINICAL QUESTION: SHOULD WE BE ADDING A DEXAMETHASONE TO NSAIDS FOR THE MANAGEMENT OF SUSPECTED ACUTE RENAL COLIC?
KEY RESULT: DEXAMETHASONE PLUS KETOROLAC WAS STATISTICALLY SUPERIOR TO KETOROLAC ALONE FOR PAIN CONTROL AT 30 MINUTES BUT NOT AT 60 MINUTES IN ADULTS WITH SUSPECTED ACUTE RENAL COLIC
Comment on Authors’ Conclusion Compared to SGEM Conclusion: We think the authors are over-interpreting their evidence. Without additional information on how accurate the diagnosis, stone size and location, rate of adverse events and use of adjunct medication we should consider this preliminary data hypothesis generating.